News

Enrolment of the 742nd and last participant in the HEMOTION trial!

Apr 13, 2023 – We are really happy to announce that The Ottawa Hospital – Civic Campus just randomized the 742nd patient! This now completes enrolment in the HEMOTION trial.

We want to thank all the research coordinators, research staff and site PIs without whom this success of enrolment would have been impossible.

One major step achieved!

Update at the joint CCCTG / CTRC winter 2023 session

Jan 26, 2023 – We presented an update on the progress of the ongoing HEMOTION trial at the recent joint session of the Canadian Critical Care Trials Group (CCCTG) and Canadian Traumatic Brain Injury Research Consortium (CTRC) meetings (Lake Louise, AB, Canada – January 26, 2023).

We warmly thank you for your support in the conduct of this trial.

700th patient recruited in Ottawa!

Dec 12, 2022 – We are very excited to announce that the 700th HEMOTION patient has been recruited today by the team at The Ottawa Hospital – Civic Campus (Canada)!

Thank you so much to all participating sites and their teams for all the efforts to reach this accomplishment. There are only 42 patients left to recruit before the end of the trial!

Thank you all for your commitment!

Update during the NCS 20th Annual Meeting in San Antonio (TX, USA)

Oct 24, 2022 – We presented an update on the progress of the HEMOTION trial at the recent Neurocritical Care Society (NCS) 20th Annual Meeting taking place October 17-21, 2022, in San Antonio, Texas (USA).

We are particularly grateful for your support in conducting this study.

Recent publication: HEMOTION clinical trial protocol

Oct 19, 2022 – The protocol of the HEMOTION multicenter, randomized clinical trial has been published in the BMJ Open: https://bmjopen.bmj.com/content/12/10/e067117

Thanks to all the researchers and teams involved in the realization of this clinical trial.

Team in Regina has randomized its first patient in HEMOTION!

Jun 27, 2022 – Congratulations to the team and investigators in Regina (Canada) for recruiting your first patient in HEMOTION today. Great job!

Thank you all for your hard work and efforts in the project.

600th patient recruited in Salford (UK)!

Jun 21, 2022 – Today, the team in Salford (UK) has enrolled the 600th patient in the HEMOTION trial.

This is another important recruitment milestone and we warmly thank our colleagues and the entire team in Salford and also all the teams in the UK, France, Brazil, Canada, who are dedicated to the HEMOTION trial and are working tirelessly to help answer the research question addressed in the HEMOTION trial. We are extremely grateful for all the efforts and energy that have gone into making this trial a success and feel privileged to have you as partners.

Thank you all for your commitment!

Update during the CCCTG / CTRC Spring 2022 meetings

Jun 2, 2022 – We presented an update on the progress of the ongoing HEMOTION trial at the recent joint session of the Canadian Critical Care Trials Group (CCCTG) and the Canadian Traumatic Brain Injury Research Consortium (CTRC) meetings (Montréal, QC, Canada – June 2, 2022).

We warmly thank all participants for their support in the conduct of this study and appreciate your feedback.

Sunnybrook and CHU de Québec – UL reach 50 and 100 patient milestones

May 30, 2022 – We are happy to highlight some milestones achieved over the last weeks:

The CHU de Québec – Université Laval team recruited their 100th patient during the month of May! What a great accomplishment!

The Sunnybrook team recruited their 50th patient at the end of the month! They are simply incredible!

HEMOTION trial has reached 75% patient enrollment!

Mar 9, 2022 – The team at The James Cook University Hospital (Middlesbrough, UK) has recruited the 534th patient corresponding to 75% enrollment.

We are delighted that despite the challenging circumstances of the past two years, HEMOTION continues as planned, reaching such a significant milestone.

We are grateful to the investigators and staff at each of the participating clinical sites in Brazil, Canada, France and UK, who continue to enroll in this trial throughout the COVID-19 pandemic.

Merci, thanks, obrigado, and congratulations to all!

75% enrolment target is coming!

Feb 18, 2022 – We are close to reaching 75% of our planed enrolment. Thank you to all of you for your contribution in reaching this goal. We can’t wait to see who will recruit this participant!

A new milestone reached: 500 patients!

Jan 13, 2022 – A new milestone has been reached. Congratulations to the team at the University of Nottingham Hospital (UK) that successfully enrolled the 500th patient in the HEMOTION Trial.

We are very grateful to all the investigators, research coordinators and local teams for your participation and commitment to the HEMOTION Trial. We couldn’t do it without you!

First patient recruited at Aintree University Hospital (Liverpool, UK)!

Dec 1, 2021 – Congratulations to the team at Aintree University Hospital (Liverpool, UK) for recruiting their first patient. Thank you for your hard work!

Congratulations to the Barretos team (Brazil) for recruiting their first patient!

Nov 16, 2021 – Congratulations to the team in Barretos (Brazil) for recruiting their first patient. Thank you for your hard work and commitment, «fantástico»!

First patient recruited in Strasbourg (France)!

Oct 25, 2021 – We are very excited to announce enrolment of the first patient by the investigators and clinical team in Strasbourg (France). Congratulations to all of our colleagues in Strasbourg for your participation and efforts in the trial!

First patient recruited at The Walton Centre (Liverpool, UK)!

Sep 22, 2021 – Congratulations to the team in Liverpool (UK) at The Walton Centre, who randomized their first participant into the HEMOTION trial. Well done team and keep up the hard work!

Team in Nîmes (France) has randomized its first patient in HEMOTION!

Sep 22, 2021 – Many congratulations to the Investigators and the team in Nîmes (France) for recruiting their first patient in HEMOTION today. Your hard work and efforts are very much appreciated.

400 patients enrolled!

Aug 17, 2021 – We are incredibly excited to share the news that the 400th HEMOTION trial participant has been recruited today. The site at St Mary’s Hospital (London, UK) had the honors of this enrolment. Many congratulations to the London team!

We would like to take this opportunity to express our gratitude to all medical professionals and teams in Brazil, Canada, France and UK, on participating in the HEMOTION trial.

We are eager to achieve our next milestone! Who will randomize the 500th patient?

São Paulo has recruited the first patient in Brazil!

Jul 1, 2021 – Congratulations to the team in São Paulo for recruiting the first patient in Brazil! Thank you very much for all your dedication to the HEMOTION trial!

Opening of the first participating site in Brazil

Jun 28, 2021 – We are very pleased to announce the activation of the first HEMOTION participating site in Brazil, in São Paulo. The São Paulo site team is led by Professor Dr. Luiz Marcelo Sá Malbouisson.

Congratulations to the entire team for all your efforts in the administrative process and your commitment despite the pandemic context.

HEMOTION trial reaches 50% enrollment milestone

Jun 16, 2021 – It is with great pleasure that today, with the help of the Sunnybrook team, we randomized our 356th patient and just reached the 50% enrollment target! Thank you to the Sunnybrook team and all the participating sites who made it happen, despite challenges posed by the COVID-19 pandemic.

We are grateful for your support and particularly appreciate the tremendous work of all the clinical investigators and teams at participating sites, in Canada, UK and France, in achieving this milestone.

Brief update during joint session CCCTG / CTRC meetings

Jun 4, 2021 – A brief update on the progress of the ongoing HEMOTION trial was presented at the Joint Session of the Canadian Critical Care Trials Group (CCCTG) and Canadian Traumatic Brain Injury Research Consortium (CTRC) on June 3rd 2021 (Virtual meeting).

Thanks for the great participation!

Team in Clermont-Ferrand (France) has enrolled its first patient!

Jun 1, 2021 – Congratulations to the team in Clermont-Ferrand (France) for recruiting its first patient into the HEMOTION trial. Thank you to every single member of the team for their hard work and dedication.

Congratulations to the Sunnybrook HSC (Toronto) team for recruiting their first patient!

Mar 29, 2021 – Congratulations to the team at Sunnybrook Health Sciences Center (Toronto, Canada) for recruiting their first patient. Thank you for your hard work!

Besançon (France), has enrolled its first patient!

Feb 18, 2021 – Congratulations to the Besançon-based team in France for enrolling their first participant into the HEMOTION trial. Thank you so much for all your dedication towards this clinical trial!

Update during CCCTG / CTRC winter 2021 joint session

Jan 21, 2021 – An update on the progress of the ongoing HEMOTION trial was presented at the recent joint session of the Canadian Critical Care Trials Group (CCCTG) and Canadian Traumatic Brain Injury Research Consortium (CTRC) meetings (Virtual meeting – January 21, 2021).

Thank you all for the discussion and reflections on the ongoing trial.

The 300th patient has been randomized!

Jan 4, 2021 – Congratulations to the team in Trois-Rivières (Québec) that successfully enrolled the 300th patient. Keep it up, and we will quickly reach our 400th patient!

With continued gratitude for the outstanding engagement of our HEMOTION teams.

New national coordinating center in France

Oct 2, 2020 – We are very happy to announce the opening of a new national coordinating center in France for the Hemotion trial. This center will be based in Besançon (Franche Comté) in partnership with the team of Dr Sébastien Pili-Floury and will aim to initiate the forthcoming recruitment of patients in the Hemotion trial in France.

Team in Halifax has randomized a first patient in HEMOTION!

Jul 17, 2020 – Many congratulations to the Investigators and the team in Halifax (Nova Scotia) for recruiting a first patient to HEMOTION today. Keep up the good work everyone!

Thank you also to the many collaborators in Canada and UK who have been busy recruiting in the last month.

Congratulations Edmonton team on recruiting at second site

May 25, 2020 – A note of congratulations for the team in Edmonton (Alberta) on opening recruitment at a second local hospital. Well done and keep up the good work!

Patient enrollment during the pandemic

May 18, 2020 – The COVID-19 pandemic has created a complex set of clinical trials recruitment challenges for teams participating in HEMOTION.

Several sites are now beginning to restart HEMOTION enrollment that they had paused in March to allow their hospital to prioritize patients with COVID-19.

Again, we want to express our heartfelt and sincere gratitude for your important contribution and your extraordinary efforts in HEMOTION, as well as thank you for your ongoing commitment to the health and safety of our patients and communities.

Update during CCCTG / CTRC winter 2020 joint session

Jan 23, 2020 – We presented an update on the progress of the ongoing HEMOTION trial at the recent joint session of the Canadian Critical Care Trials Group (CCCTG) and Canadian Traumatic Brain Injury Research Consortium (CTRC) meetings (Lake Louise, AB, Canada – January 23, 2020).

We warmly thank you for your support in the conduct of this study and appreciate your comments.

The 200th patient has been randomized!

Jan 9, 2020 – Congratulations to the team in Cardiff (UK) that successfully enrolled the 200th patient.

We would like to thank all of our collaborators on the HEMOTION Trial for all of their superb efforts up to this point. Keep up the good work and hopefully it won’t be long before we hit our 300th patient!

First patient recruited in Stoke-on-Trent (UK)!

Dec 10, 2019 – Congratulations to the team in Stoke-on-Trent (UK), who randomized their first participant into the HEMOTION trial. Well done team and keep up the hard work!

London (UK), has enrolled its first patient!

Dec 2, 2019 – Congratulations to the London-based (St Mary’s) team for enrolling their first participant into the HEMOTION trial. Thank you so much for all your dedication towards this clinical trial!

A new milestone achieved in the HEMOTION trial: 25% of recruitment!

Nov 15, 2019 –  Today, 178 patients have been successfully randomized into the trial, reaching the 25% goal. Patient 178 was randomized by St. Michael’s team in Toronto (Canada) on Friday, November 15th.

We would like to thank all the study teams for their interest and their commitment to the HEMOTION trial, whether you are one of the top recruiters or more recent recruiters in Canada and the UK, or have expressed the wish to become one of them soon.

Together, we can do more!

Edinburgh (UK), first patient recruited!

Oct 23, 2019 – Congratulations to the team in Edinburgh, Scotland (UK), who randomized their first participant into the HEMOTION trial. Well done team!

Congratulations to the teams in Toronto (Canada) and Edmonton (Canada) on recruiting their first patients!

Sep 3, 2019 – Well done to the teams in Toronto (St. Michael’s Hospital) and Edmonton (University of Alberta Hospital) who recruited their first patients in August and also to Montreal (CHUM) who started screening.

Winnipeg (Canada) and Middlesbrough (UK) have enrolled their first patients!

Aug 26, 2019 – New sites in Winnipeg (Canada) and in Middlesbrough (UK) have started recruitment and enrolled their respective first patient in the HEMOTION clinical trial. Congratulations to both for your hard work!

Recent presentations of the HEMOTION trial

Jun 26, 2019 – We presented an update of the HEMOTION trial at several meetings in the last two months. Many potential collaborators from different countries showed interest in joining forces and run the HEMOTION trial at their site.

PRATO 2019 – Collaborative Clinical Trials in Intensive Care Medicine Conference
Prato (Italy) – June 6, 2019
The trial was presented to international colleagues to establish eventual collaboration.

CCCTG and CTRC
Niagara-on-the-Lake (Canada) – June 13, 2019
We presented a trial update at the CCCTG/CTRC joint session. We are grateful for your support of the trial and really appreciate your valuables comments.

PACT – Canadian Perioperative Anesthesia Clinical Trials
Calgary (Canada) – June 20, 2019
An update was presented at the PACT meeting in Calgary. The collaboration with PACT has been great and helpful with our anesthesia colleagues considering that our patients often require surgery.

100th patient recruited today!

Jun 18, 2019 – The HEMOTION clinical trial has achieved a significant milestone by recruiting its 100th patient today. The patient was enrolled at the Montreal General Hospital (MGH) in Montreal (Quebec, Canada). This is a wonderful result achieved through hard work and cooperation among the sites, RCs, study teams, principal investigators and the coordinating center.

We extend our congratulations and thanks to all teams involved for your ongoing collaboration!

Nottingham (UK) has enrolled its first patient!

Jun 14, 2019 – New site in Nottingham (UK) has started recruitment and enrolled its first patient in the HEMOTION clinical trial. Congratulations on a job well done!

First patients recruited in Cardiff (UK) and in Victoria (Canada)

May 10, 2019 – This week, our colleagues in Cardiff (UK) and in Victoria (Canada) have both enrolled their first patient in the HEMOTION trial at their respective centers. For the team in Cardiff this is also the first patient enrolled in the UK!
Great team efforts, thank you all!

HEMOTION trial website is launched!

Apr 10, 2019 – This website is part of the communication tools of the HEMOTION clinical trial. Our aim is to provide clear and concise information on this clinical trial through a simplified and user-friendly website.

Start meeting of the HEMOTION trial

The HEMOTION Inception Meeting was held in Lake Louise, Alberta on January 22, 2018. Researchers and research coordinators from several participating Canadian centers attended the meeting. Drs. Alexis Turgeon, Dean Fergusson and François Lauzier are the principal investigators in this multicenter randomized controlled trial to establish the optimal transfusion strategy in patients with moderate to severe traumatic brain injury.

Recruitment for the HEMOTION trial at CHU de Québec-Université Laval

Recruitment for the HEMOTION trial is progressing very well at the CHU de Québec-Université Laval. We exceeded our target of 1-2 patients per month! We look forward to starting this new trial in other sites in Canada and United Kingdom!

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